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5 Best Topical Treatments of 2025

Last Updated - 26/08/2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

MANUAL

Manual 5% Minoxidil (3 x 60ml) Formula For Men - Increases Blood Flow To Follicles - Promotes Growth for Longer, Thicker Hair - Stimulates Hair Regrowth - Easy To Apply Spray - 3 Month Supply

MANUAL

£49.99

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- WHY CHOOSE MANUAL: We're not only UK-licensed experts, but a brand you can trust. MANUAL is revolutionising hair loss treatment to help You get Your hair back and feel more confident than ever. More than 200,000 men trust our treatment, thanks to personalised hair loss plans and clinicians on-hand to maximise your success. What are You waiting for? Your hair regrowth journey starts today.
- TARGETED HAIR LOSS TREATMENT: At MANUAL, we combine science, technology and medical expertise to deliver personalised, cutting-edge hair loss treatment that put an end to hair loss. Minoxidil, one of our most popular medical treatments, and is scientifically proven to effectively treat hair loss and stimulate regrowth. With targeted treatments, expert advice and unlimited free support, there's a reason over 200,000 people trust our hair loss plans.
- HOW TO APPLY THE SOLUTION: Firstly, aim for the scalp rather than the hair, as this is where the follicles are and it's the follicles that benefit from the treatment. Secondly, avoid dripping and wasting the solution by tilting Your head backwards to avoid getting the solution in Your eyes. Remember to time Your dosages and only use it twice a day. Don't forget to wash Your hands!
- HOW MINOXIDIL WORKS: DHT (a male hormone) shrinks Your follicles which causes hair thinning and eventually baldness. Minoxidil works as a vasodilator, widening blood vessels in the scalp to encourage blood flow to the area. This means more nutrients and oxygen reach Your scalp, helping to bring follicles back to health. Minoxidil works to reset the cycle of Your follicles, meaning that the growth phase is longer, resulting in thicker, healthier hair.
- EFFECTIVE RESULTS OVER TIME: Minoxidil is not a medication that works overnight. Although it's a very effective treatment, it will take time to encourage Your hair follicles to return to health. For effective results, be consistent and make sure the treatment is part of Your daily routine. Studies suggest that results are best seen after 4 - 6 months.
£49.99
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Kusuri

Topical Treatment Kit - Kusuri 8 Piece Kit

Kusuri

£49.95

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- A complete easy to use kit, for the beginner or experienced fish keeper. For treating Ulcers, wounds and Fin Rot All kit components are replaceable, so you need never run short of any particular item.
£49.95
3
18% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Scholl
18% Off

Scholl Fungal Nail Treatment, 3.8 ml - Fungal Nail Infection Treatment and Prevention Kit, Includes 3.8ml Liquid and 5 Disposable Nail Files , Pack of 1

Scholl

£16.34

£19.99
(18% Off)

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- UNIQUELY DESIGNED: Scholl's Fungal Nail Treatment Kit is uniquely designed for the treatment of fungal nail in 2 steps. Firstly, kit contains an advanced liquid formulation to fight infection at the source (based on observational data). Secondly, unique one way file dispense mechanism contains disposable files to help prevent spread of infection
- IMPROVEMENTS FROM TWO WEEKS: Of unsightly nail fungus symptoms with continuing improvements throughout fungal nail treatment
- EFFECTIVELY TREATS AND HELPS PREVENT: Scholl Fungal Nail Treatment works to treat the early signs of fungal nail and also helps prevent the spread of infection to protect against re-occurrence
- DISPOSABLE FILES: Filing your nail provides long lasting results as the advanced liquid penetrates in to the nail (based on vitro data). The unique one way file dispense mechanism contains disposable files to help prevent spread of infection
- CLINICALLY PROVEN: Scholl's Fungal Nail Treatment has been scientifically and clinically proven to treat fungal nail. Always read the instructions. Treatment can take 9-12 months for infected nail to fully grow out
£16.34
£19.99 (18% Off)
4
Best Value
25% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

E45
25% Off

E45 Psoriasis Cream 50 ml – Treatment for Psoriasis Symptoms – to Reduce Scaling, Itching, Redness, Roughness, Dry, Hard Skin – Moisturising E45 Cream – Relieve Irritated Skin

E45

£14.95

£19.99
(25% Off)

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- WHAT IS PSORIASIS? – Psoriasis is a long-lasting skin condition which causes flaky patches of skin which form scales. These patches can appear anywhere on the body but most commonly the elbows, knees, scalp, and lower back. They can look pink or red and the scales white or silvery, and on darker skin the patches can look purple or dark brown with grey scales. The patches can be sore and itchy. E45 Psoriasis Cream is intended for the treatment and prevention of psoriasis and dermatitis symptoms.
- TREAT SYMPTOMS OF PSORIASIS – E45 Psoriasis Cream has been formulated to treat and prevent psoriasis and dermatitis symptoms and has been scientifically proven to reduce scaling itching, redness, roughness and hardening of the skin. The moisturising cream is full of nourishing ingredients that hydrate and stabilise the skin’s barrier, as well as supporting the skin’s natural regeneration process. It helps with dry, itchy, red, flaky skin and reduces roughness and hardening of psoriasis plaques.
- REDUCE INFLAMMATION - E45 Psoriasis Cream contains Ectoin, a natural cell-protective molecule with inflammation-reducing and membrane-stabilising properties. Our Cream relieves and calms irritated and damaged skin by reducing inflammatory reactions and supporting the regeneration process of the skin. This cream is suitable for long term use and is a steroid-free psoriasis treatment. It should be gently massaged into the affected areas of skin 3 times a day or as often as needed.
- QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
- HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
£14.95
£19.99 (25% Off)
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

NT Labs

NT Labs Koi Care Paramedic Kit, Topical Treatment Kit for Koi, Treats Cuts, Abrasions and Ulcers on Koi, Contains Koi Calm, Ulcer Swab and Propolis Wound Seal.

NT Labs

£18.74

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- 【 TREATMENT RULES 】: Do not use in hot, humid, thundery weather. Do not leave fish unattended during treatment.
- 【 TOPICAL TREATMENT KIT FOR USE ON KOI 】: The Paramedic Kit is designed to be used when fish have cuts, abrasions or ulcers on their body. The Paramedic Kit has been designed to allow you to carry out basic first aid on your koi safely and hygienically to help fish recover as quickly as possible.
- 【 THE LEADING RANGE OF KOI CARE PRODUCTS 】: The most highly regarded range of koi products in the industry, trusted for 40 years by both trade customers and consumers alike, this range effectively cares for and protects koi in the environment in which they live. From products that treat parasitic or bacterial infections to a tap water dechlorinator, the NT Labs Koi Care range offers koi enthusiasts everything they could possibly need to keep perfect koi and an equally perfect koi pond.
- 【 EASY TO USE】: Ensure you have the appropriate equipment ready before catching the injured fish. This should include a container large enough to hold the fish during treatment. Follow the instruction on the leaflet provided. Treat the pond with Acriflavin after using this kit to reduce the numbers of pathogenic bacteria and to reduce the likelihood of re-infection of the wounds. Feed your fish Medikoi Health and Medikoi Probiotic to aid their recovery by providing vital nourishment and high-quality nutrition. Test your water quality regularly using NT Labs Test Kits.
- 【 ALL IN ONE EMERGENCY KIT 】: Each box contains 10ml Koi Calm: a sedative to make fish easier to handle (for use with koi only). 30ml Ulcer Swab: A wound cleaner and disinfectant. 30ml Propolis Wound Seal: an antiseptic, waterproof sealant to prevent bacteria reaching the wound. Pair of gloves: to maintain hygiene during treatment. 10 Cotton Buds: for applying topical treatments. Instruction Leaflet: contains advice on how to use the products within the kit.
£18.74

5 Best Topical Treatments of 2025

Manual 5% Minoxidil (3 x 60ml) Formula For Men - Increases Blood Flow To Follicles - Promotes Growth for Longer, Thicker Hair - Stimulates Hair Regrowth - Easy To Apply Spray - 3 Month Supply

Topical Treatment Kit - Kusuri 8 Piece Kit

Scholl Fungal Nail Treatment, 3.8 ml - Fungal Nail Infection Treatment and Prevention Kit, Includes 3.8ml Liquid and 5 Disposable Nail Files , Pack of 1

E45 Psoriasis Cream 50 ml – Treatment for Psoriasis Symptoms – to Reduce Scaling, Itching, Redness, Roughness, Dry, Hard Skin – Moisturising E45 Cream – Relieve Irritated Skin

NT Labs Koi Care Paramedic Kit, Topical Treatment Kit for Koi, Treats Cuts, Abrasions and Ulcers on Koi, Contains Koi Calm, Ulcer Swab and Propolis Wound Seal.

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Sons Minoxidil 5% Cutaneous Solution and Dermaroller, Hair Regrowth Treatment. For Hair Loss & Thinning in Men. Microneedling Stimulates Collagen and Reactivates Shrunken Follicles. Made in Europe.

NT Labs Koi Care Propolis Wound Seal, Koi Medicine, Topical Treatment for Ulcers, Open Wounds, Damaged Fins and Hikui, Natural Product, Bee Propolis, 30ml

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Excilor Fungal Nail Infection Treatment | Clinically Proven | Contains Biotin Supporting Repair & A Stronger Nail Barrier Against Fungus | Visible Results In 2 Weeks | No Filing | Fast-Drying | 3.3ml

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Acnecide Face Gel 5% Benzoyl Peroxide Acne Treatment for Spot Prone Skin 15g

Azelaic Acid Face Cream,Brightening Face Skin Care Treatment,Azelaic acid 12% face serum,Faded Topicals for Dark Spots,face anti-aging serum, suitable for all skin types (20g, 2PC)

Pinewoods Fast Acting Hydrocortisone Cream 1% w/w Bite and Sting Cream, Mosquito and Bee Sting Treatment, Itchy Skin and Redness Solution, 3 x 10g Tubes for Eczema and Irritation

Brulidine Antiseptic and Antibacterial Cream 25g

Psecici Scar Cream, Silicone Scar Gel,Scar Cream for Surgical Scars,Burn,Acne,Stretch Mark,Keloid Bump,C Section Scars

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